On Madden D there are specific plays that don't work as well as they should. Even though Madden NFL 10 has impressive realism, certain alignments still aren't up to standards in terms of matching their real-life realism.
Engage Eight; a popular eight man blitz in almost every defensive playbook, this almost always happens too unsurprisingly and it's hard to align the few cover players efficiently, almost leaving opponents open and not getting people to the signal caller nearly quick enough.
3-4 Defense; Although moderately improved in Madden NFL 10, the 3-4 has always felt like an inferior defense in Madden, as it hasn't properly replicated the confusion and chaos the defense intices. Also, creating a bad-ass run-stopping NG is something that is difficult to do on a game like Madden.
Prevent Defense; In the real NFL players would never let the last player get behind them. Somehow in Madden prevent defense is less effective than in real life, where it is horrible as well. Because of the zone alignment you can easily get 1 vs 1 deep and often beat the coverage. Because of this, it is always a greater idea to do man coverage and align your players deep.
Fake-Punt Passes; Madden hasn't been able to accurately give throwing accuracy/power to non quarterbacks, making their chucking ability unrealistically pourus. This applies to the Wildcat formation as well where runningbacks/wide receivers can't throw even decently well, and seem like they haven't tossed a rock in their lives.
Madden is a constantly improving game but it seems like the developers have never been able to solve some of these problems, even though they've persisted throughout the history of Madden. If they ever fix these defensive and also the offensive problems that hurt it, it will come super close to a pure football simulation that is for sure capable of.
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