Factor XI (FXI) deficiency is a disorder autosomal which can be associated the bleeding. Factor XI deficiency is a very rare disorder which functions in the families. It has like consequence the weak coagulation of blood. The two parents must be carriers to pass it to their children. Family antecedents of a disorder of bleeding are a factor of risk. Factor XI deficiency is common and results from a lack of the vitamin K, hepatic affection engraves, and of the use of drugs which prevent to coagulate. The factors of risk for the insufficiency of the vitamin K are long-term use of antibiotics, obstruction cholagogue, and weak absorption of food of the intestinal area.

Some new-born is constant with the insufficiency of the vitamin K. Signs and the symptoms change with the level of the prothrombine. The patients having the levels 50% larger than normal do not have any problem of bleeding, while people with levels from 2% to 50% can easily meurtrir or suffer from the epistaxis, menorrhagia, haemorrhages of muscle, the postpartum bleeds and haemorrhage after surgery and trauma. Factor XI (FXI) deficiency can be treated with the complex concentrates of prothrombine (PCCs). If necessary, it can be treated with the therapy of replacement of plasma.

The therapy of antifibrinolytic was employed in the treatment of the women with the insufficiency and the menorrhagia of FXI. Blood loss can be controlled by getting fresh or frozen plasma or concentrates of clotting factors into the blood. The pregnant women will require for fresh frozen plasma if the delivery caesarean is projected. The treatment of Peripartum of the women with the insufficiency of FXI is discussed. The genetic consultation can be salutary for the disorders which start with the birth. Long-term antibiotic use may help prevent problems. Bleeding has to be managed in example trauma or surgery.

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