http://www.articlealley.com en-us editorial@articlealley.com Despite intense interest and scrutiny focused on FOXP3 as a key protein & master transcription factor, isolating and enriching for viable FOXP3 positive cells remains a challenge. Although cell separation/staining via CD4+CD25+ selection is commonly use... http://www.articlealley.com/article_701599_17.html 01st December 2008 Neuropilin-1 (Nrp-1) was recently identified as a possible surface marker for naturally occurring CD4+CD25+ regulatory T cells and is constitutively expressed on the cell irrespective of its activation status. Nrp-1 is a type 1 membrane protein with thre... http://www.articlealley.com/article_701597_17.html 01st December 2008 Folates play an important role in protein and nucleic acid biosynthesis and are particularly recognized for their roles in spinal canal and brain development during early pregnancy. FR4 is expressed at high levels on both natural and TGF-b induced Tregs. ... http://www.articlealley.com/article_701595_17.html 01st December 2008 Neuropilin-1 (Nrp-1) was recently identified as a possible surface marker for naturally occurring CD4+CD25+ regulatory T cells and is constitutively expressed on the cell irrespective of its activation status. Nrp-1 is a type 1 membrane protein with thre... http://www.articlealley.com/article_629710_17.html 09th September 2008 Tumor metastasis plays a key role in assessing treatment strategies and an important factor in determining patient prognosis. Not surprisingly, significant effort has been focused on elucidating the molecular basis behind tumor metastasis. This understa... http://www.articlealley.com/article_629709_17.html 09th September 2008 Toll-like receptor 10 (TLR10) often known as CD290 (cluster of differentiation 290), is the most recently identified human homolog of the Drosophila TOLL protein. Human TLR10 is an orphan member of the Toll-like receptor family that recognizes pathogen-as... http://www.articlealley.com/article_517776_23.html 16th April 2008 Toll-like receptor 9 (TLR9) often known as CD289 (cluster of differentiation 289), is a member of the Toll-like receptor family that recognizes pathogen-associated molecular pattern. TLR9 was first cloned and identified as a receptor for unmethylated CpG-... http://www.articlealley.com/article_517775_23.html 16th April 2008 Toll-like receptor 7 (TLR7), is an immune gene possessed by humans, other mammals and additionally in avian species playing a significant role in initiating antiviral immune responses. It belongs to the evolutionarily conserved Toll-like receptor family. ... http://www.articlealley.com/article_517773_23.html 16th April 2008 Toll-like receptor 4 (TLR4) often designated as CD284 (cluster of differentiation 284) is a class I transmembrane receptor belonging to the large homologous family of Toll like receptors. TLR4 expressed on the surface of immune system cells, is activated ... http://www.articlealley.com/article_517769_23.html 16th April 2008 Toll-like receptor 3 (TLR3) often designated as CD283 (cluster of differentiation 283) is a type I transmembrane receptor protein. It belongs to a family of evolutionary conserved innate immune recognition molecules and recognizes double-stranded RNA, a ... http://www.articlealley.com/article_517766_23.html 16th April 2008 Toll-like receptor 2 (TLR2), often designated as CD282 (cluster of differentiation 282) is a type I transmembrane protein belonging to the large homologous family of Toll like receptors. TLR2 acts as functional receptor for both Gram-positive and Gram-neg... http://www.articlealley.com/article_517714_23.html 16th April 2008 Toll-like receptor 1 (TLR1) often designated as CD281 (cluster of differentiation 281), a member of the Toll-like receptor family recognizes pathogen-associated molecular pattern with specificity for gram-positive bacteria. TLR1 is a 786-residue type I tr... http://www.articlealley.com/article_517713_23.html 16th April 2008 Toll-like receptor 10 (TLR10) often known as CD290 (cluster of differentiation 290), is the most recently identified human homolog of the Drosophila TOLL protein. Human TLR10 is an orphan member of the Toll-like receptor family that recognizes pathogen-as... http://www.articlealley.com/article_515406_17.html 11th April 2008 Toll-like receptor 9 (TLR9) often known as CD289 (cluster of differentiation 289), is a member of the Toll-like receptor family that recognizes pathogen-associated molecular pattern. TLR9 was first cloned and identified as a receptor for unmethylated CpG-... http://www.articlealley.com/article_515405_17.html 11th April 2008 Toll-like receptor 8 (TLR8) often designated as CD288 (cluster of differentiation 288) is a member of evolutionarily conserved Toll-like receptor family which are critical parts of the evolutionarily conserved innate immune system. TLR8 has been identifie... http://www.articlealley.com/article_515404_17.html 11th April 2008 Toll-like receptor 7 (TLR7), is an immune gene possessed by humans, other mammals and additionally in avian species playing a significant role in initiating antiviral immune responses. It belongs to the evolutionarily conserved Toll-like receptor family. ... http://www.articlealley.com/article_515403_17.html 11th April 2008 Toll-like receptor 6 (TLR6) often designated as CD286 (cluster of differentiation 286), is a member of the Toll-like receptor family, a highly conserved series of ancient innate immune pattern recognition receptors. TLR6 was first described by Takeuchi et... http://www.articlealley.com/article_515402_17.html 11th April 2008 Toll-like receptor 5 (TLR5), a member of the evolutionarily conserved Toll-like receptor family, has evolved to permit mammals specifically to detect flagellated bacterial pathogens. Like all other members of the TLR family, TLR5 is composed of an extrace... http://www.articlealley.com/article_515401_17.html 11th April 2008 Toll-like receptor 4 (TLR4) often designated as CD284 (cluster of differentiation 284) is a class I transmembrane receptor belonging to the large homologous family of Toll like receptors. TLR4 expressed on the surface of immune system cells, is activated ... http://www.articlealley.com/article_515399_17.html 11th April 2008 Toll-like receptor 3 (TLR3) often designated as CD283 (cluster of differentiation 283) is a type I transmembrane receptor protein. It belongs to a family of evolutionary conserved innate immune recognition molecules and recognizes double-stranded RNA, a ... http://www.articlealley.com/article_515398_17.html 11th April 2008 Toll-like receptor 2 (TLR2), often designated as CD282 (cluster of differentiation 282) is a type I transmembrane protein belonging to the large homologous family of Toll like receptors. TLR2 acts as functional receptor for both Gram-positive and Gram-neg... http://www.articlealley.com/article_515397_17.html 11th April 2008 Toll-like receptor 1 (TLR1) often designated as CD281 (cluster of differentiation 281), a member of the Toll-like receptor family recognizes pathogen-associated molecular pattern with specificity for gram-positive bacteria. TLR1 is a 786-residue type I tr... http://www.articlealley.com/article_515396_17.html 11th April 2008 The p53 family member, p73, also known as tumor protein 73 (TP73) has been recently identified as a structural and functional homolog of the tumor suppressor protein p53. In accordance with its structural similarity, p73 functions in a manner analogous to... http://www.articlealley.com/article_486885_23.html 07th March 2008 The cytoskeleton is a network of fibers throughout the cell's cytoplasm that helps the cell maintain its shape and gives support to the cell. It is a cellular scaffolding or skeleton contained within the cytoplasm, present in both eukaryotes and prokaryot... http://www.articlealley.com/article_486884_23.html 07th March 2008 The p53 family member, p73, also known as tumor protein 73 (TP73) has been recently identified as a structural and functional homolog of the tumor suppressor protein p53. In accordance with its structural similarity, p73 functions in a manner analogous to... http://www.articlealley.com/article_486233_23.html 07th March 2008 The cytoskeleton is a network of fibers throughout the cell's cytoplasm that helps the cell maintain its shape and gives support to the cell. It is a cellular scaffolding or skeleton contained within the cytoplasm, present in both eukaryotes and prokaryot... http://www.articlealley.com/article_486230_23.html 07th March 2008 Immunology is a broad branch of biomedical science that covers the study of all aspects of the immune system in all organisms. The immune system is the body's defense against infectious organisms and other invaders. Through a series of steps called the im... http://www.articlealley.com/article_236251_23.html 05th November 2007 RNA interference (RNAi) is the process of mRNA degradation that is induced by double-stranded RNA in a sequence-specific manner. RNAi has been observed in all eukaryotes, from yeast to mammals. The RNAi pathway is thought to be an ancient mechanism for pr... http://www.articlealley.com/article_236275_23.html 05th November 2007